The article discusses desertification in Africa, focusing on the complex relationships between environmental and social factors. It presents new perspectives on measuring desertification and highlights the role of land tenure and poverty in land degradation. Case studies from Botswana, South Africa, and Ethiopia show how different factors impact plant diversity, soil quality, and the spread of diseases like malaria. The research suggests that changes in land use practices can have significant effects on the environment and human health in African regions.