Medicine
8 years ago

Thyroid Hormones Independently Regulate Brain's Thyrotropic Center mRNA Levels

Molecular Endocrinology
Thyroid Hormone Regulation of Messenger Ribonucleic Acid Encoding Thyrotropin (TSH)-Releasing Hormone is Independent of the Pituitary Gland and TSH
R. Thomas Zoeller, R Wolff, Kerry J. Koller

Paper Summary

Related papers

Theme background image
Medicine
8 years ago

Thyroid Hormones Independently Regulate Brain's Thyrotropic Center mRNA Levels

Thyroid Disease
Insulin-like Growth Factors
Stress Effects
1 view
Theme background image
Neuroscience
8 years ago

New study reveals peptide's role in controlling thyroid hormone levels.

Neuropeptides
Puberty Regulation
Urotensin II
Theme background image
Medicine
8 years ago

New study shows TRH infusion prevents hypothyroidism in rats

Thyroid Disease
Insulin-like Growth Factors
Puberty Regulation

Thyroid hormones can reduce the production of a hormone called TRH in the brain. Scientists wanted to see if this effect depends on the pituitary gland or another hormone called TSH. They studied rats that had their pituitary glands removed and found that thyroid hormones still decreased TRH levels in the brain, even when TSH was replaced. This shows that the control of TRH production by thyroid hormones in the brain does not need the pituitary gland or TSH.