In this study, researchers aimed to understand the role of the pituitary gland and adrenal cortex in growth hormone resistance in rats with diabetes. They made rats diabetic and then removed either the pituitary gland or adrenal glands to see their effects. The results showed that diabetic rats responded better to growth hormone after pituitary or adrenal gland surgeries. Rats without adrenal glands displayed improvements in blood sugar levels and growth when given growth hormone. Giving corticosterone, a hormone from adrenals, partially reversed these benefits. This suggests that the pituitary gland and adrenal cortex play key roles in the growth issues and growth hormone resistance seen in rats with diabetes.