Neuroscience
8 years ago

Hormones Discovered to Suppress Thyroid Function, Raising Metabolism Concerns

Experimental and Clinical Endocrinology & Diabetes
Effects of Growth Hormone-Releasing Hormone and Corticotropin-Releasing Hormone on the Release of Thyrotropin-Releasing Hormone from the Rat Hypothalamus in Vitro
T Mitsuma, T Nogimori, Y Hirooka

Paper Summary

The study looked at how growth hormone-releasing hormone (GRH) and corticotropin-releasing hormone (CRH) affect the release of a hormone called thyrotropin-releasing hormone (TRH) in the rat brain. They found that both GRH and CRH can reduce the release of TRH from the rat brain in a dose-dependent manner. This suggests that GRH and CRH have an inhibitory effect on TRH release in the rat brain when studied in a lab setting.

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