Chemistry
8 years ago

New study finds gel capsules less effective than solution for drug absorption.

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Biopharmaceutics & Drug Disposition
Study of the bioavailability of different formulations of 8-methoxypsoralen in the dog
Johan Monbaliu, F. Belpaire, Matthias Bogaert

Paper Summary

The researchers studied how well a drug called 8-methoxypsoralen is absorbed in dogs when given in different forms. They found that the drug was absorbed more quickly and effectively when given as a solution compared to gelatin capsules. Some dogs had more than 100% of the drug absorbed, showing variability between individuals. In another test, the solution form of the drug was absorbed faster and better than an emulsion form.

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