Breakthrough Technique Reduces Polyspermy in Pig IVF, Boosting Fertility
The study looked at how pig eggs are fertilized in a lab setting and how oviduct cells can affect the number of sperm that enter the egg. When eggs were fertilized without oviduct cells, many eggs had multiple sperm entering them. But when sperm and oviduct cells were cultured together for 2.5 hours before fertilization, the rate of multiple sperm entering eggs decreased by 40-50%. A longer culture time of 3.5 hours further reduced the number of eggs with multiple sperm, but also decreased the overall fertilization rate. This shows that oviduct cells can help prevent multiple sperm from entering eggs during fertilization in pigs.