The Slug protein plays a crucial role in the skin by helping with skin development, hair growth, wound healing, and protecting against sunburn. It is mainly found in basal keratinocytes and hair follicles, where it helps maintain healthy skin. Slug is activated by various growth factors and harmful substances, controlling how skin cells change, stick together, move, and produce inflammation. This protein influences how skin cells interact with their surroundings and neighboring cells. Slug's function in the skin is different from a similar protein called Snail.