Medicine
8 years ago

Adrenal Hormones Unlock Obesity Pathway, Offering New Treatment Possibilities

AJP Regulatory Integrative and Comparative Physiology
Hypothalamic obesity after hypophysectomy or adrenalectomy: dependence on corticosterone
Barbara King, Rachael L. Smith

Paper Summary

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Adrenal Hormones Unlock Obesity Pathway, Offering New Treatment Possibilities

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Neuroscience
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Removing Stress Hormones Boosts Brain's Anxiety Regulator

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The study compared the effects of removing the adrenal glands or pituitary gland on weight gain in rats with brain lesions. Complete removal of the adrenal glands stopped weight gain after brain lesions, while removal of the pituitary gland partially stopped weight gain. Rats with low levels of stress hormones gained weight after brain lesions, showing that these hormones play a role in causing obesity.