The researchers compared the structures of similar proteins, one that works alone or in a group, and another that works in a group with different proteins. They found that the group-working proteins have more similar parts at their meeting points than the solo-working ones. Also, the group-working proteins' meeting points are more likely to be oily. This difference might be because the solo-working proteins have a balanced structure that the group-working ones don't have. They used this information to predict how some human proteins interact in a complex that processes RNA. The predictions matched what was already known.