Decision Sciences
8 years ago

Observational studies show similar treatment effects as randomized trials: study.

American Journal of Ophthalmology
A comparison of observational studies and randomized, controlled trials
Kjell Benson, Arthur J. Hartz

Paper Summary

Related papers

Economics, Econometrics and Finance
2 years ago

Non-randomized studies for COVID-19 drugs may mislead regulatory decisions.

Quality of Life
COVID-19
Evidence Synthesis
Economics, Econometrics and Finance
7 years ago

Observational studies show similar treatment effects as randomized trials, debunking previous claims.

Quality of Life
Evidence Synthesis
Clinical Trials
Decision Sciences
8 years ago

Observational studies revolutionize surgical research with ethical and feasible solutions.

Evidence Synthesis
Cardiac Risk Assessment
Clinical Guidelines

Observational studies and randomized, controlled trials were compared to see if they find different treatment effects. Researchers looked at 19 treatments like calcium-channel blockers for heart disease and found that in most cases, the treatment effects were similar between the two types of studies. Only in 2 out of 19 cases did the results differ significantly. This suggests that recent observational studies are not consistently showing larger or different treatment effects compared to randomized, controlled trials.