The study looked at different fertilization methods for couples struggling with infertility during in vitro fertilization (IVF) treatment. They found that using a method called ICSI can improve fertilization rates and increase the chances of getting pregnant, especially for couples who have been trying to conceive for a long time. In particular, ICSI was more effective than traditional IVF for couples with longer infertility periods. This research suggests that using ICSI during IVF can be a beneficial option for couples facing primary infertility without a clear cause.