This paper discusses how to design flexible factory layouts for easily changing manufacturing setups. The researchers use a method called axiomatic design, focusing on two key principles: independence and information. They break down the overall goal of the layout into smaller parts and create equations for each step. They summarize the functional structure resulting from this breakdown. By applying the information principle, they calculate how much interdependence or coupling is present in the design. The study presents solutions to design challenges based on these principles, offering a systematic way to plan layouts for reconfigurable manufacturing systems.