Mice given Vanadium had lower sperm quality, but treating them with Modified Tianxiong Powder (MTP) improved it. The Vanadium-exposed mice had decreased sperm quantity, survival, and motility, with more deformities. After MTP treatment, the sperm quality of the treated mice was like the normal group. MTP also raised testosterone levels in the treated mice. This shows that MTP can help male mice with Vanadium-related sperm issues.