Biochemistry, Genetics and Molecular Biology
8 years ago

Combination therapy slashes blood sugar levels in non-insulin dependent diabetes.

PubMed
[Clinical study of glibenclamide in combination with kelening treatment in non-insulin dependent diabetes mellitus].
Peihua Zhou

Paper Summary

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Combining glibenclamide and Kelening is more effective in treating non-insulin dependent diabetes mellitus (NIDDM) than using glibenclamide alone. After 12 weeks of treatment, patients in the glibenclamide-Kelening group showed significant reductions in fasting and postprandial blood glucose levels, as well as HBA1C levels. This combination therapy also led to a greater decrease in hyperinsulinemia compared to using glibenclamide alone. Overall, the combination of glibenclamide and Kelening is more effective, less toxic, and may allow for a lower dosage of glibenclamide in treating NIDDM.