Biochemistry, Genetics and Molecular Biology
8 years ago

Weighted p-Values Boost Power in Genetic Linkage Detection for Diseases.

Genetic Epidemiology
Use of Weighted p‐Values in Regional Inference Procedures
Xiaohong R. Yang, Alisa M. Goldstein, Gary A. Chase, Joseph L. Gastwirth, Lynn R. Goldin

Paper Summary

Related papers

Theme background image
Engineering
8 years ago

New Study Reveals Sound Levels More Accurate Than Weighted Noise Data

Health Monitoring
Acoustic Metamaterials
Noise Pollution
2 views
Theme background image
Agricultural and Biological Sciences
8 years ago

New noise-weighting functions for animals could revolutionize wildlife conservation efforts.

Evolutionary Ecology
Avian Ecology
Gut Health
Theme background image
Health Professions
8 years ago

New F-Weighting System Improves Assessment of High-Level Complex Noise

Noise Pollution

The researchers tested a new method to improve the power of detecting genes linked to certain traits. They analyzed data from extended families to find genes related to two traits. By giving more weight to certain p-values, they found that the new method sometimes increased power, similar to using multiple points for analysis. However, not all weighting schemes were consistently better than others.