The article explores why regional integration systems change during economic crises in Europe, Latin America, and Asia. It looks at how financial crises affect the level of integration in different regions and what factors drive these changes. The researchers use a neo-institutionalist framework to analyze power dynamics between member states, institutions, and citizens' attitudes towards integration. The findings show that economic crises can lead to both more and less integrated regional systems, depending on various factors. This research is valuable for scholars, students, and policymakers interested in regional integration and international relations.