Melatonin treatment prevents hormone loss during bleeding in male rats.
Melatonin treatment in male rats reduces vasopressin and oxytocin levels in the brain. Bleeding also lowers these levels in untreated rats. However, bleeding does not further decrease vasopressin and oxytocin in melatonin-treated rats. This suggests that melatonin may affect how the brain responds to bleeding by regulating these hormone levels.