Medicine
8 years ago

PGE1 partially inhibits insulin release, potential breakthrough in diabetes treatment.

PubMed
[Inhibitory effect of PGE1 on the liberation of insulin induced by glibenclamide].
A. Villar, Pilar D’Ocón, Elsa Anselmi

Paper Summary

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PGE1 partially inhibits insulin release induced by glibenclamide, but doesn't completely stop it. This inhibition affects blood sugar levels too. The study suggests that diabetes-related insulin release issues might be linked to excessive PG production, which interferes with beta-cells responding to glucose signals. Glibenclamide's effectiveness in treating diabetes isn't affected by PGE1.