Biochemistry, Genetics and Molecular Biology
8 years ago

Duplicated genes in plants evolve independently, leading to functional diversity.

Scientific Reports
Imbalanced positive selection maintains the functional divergence of duplicated DIHYDROKAEMPFEROL 4-REDUCTASE genes
Bing-Hong Huang, Yi-Wen Chen, Chia-Lung Huang, Jian Gao, Pei‐Chun Liao

Paper Summary

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Gene duplication of DIHYDROFLAVONOL 4-REDUCTASE (DFR) in plants like Scutellaria can lead to different functions between the duplicates. The duplicates evolved at different rates due to positive selection, resulting in changes in gene expression and amino acids. This suggests that the duplicates have adapted to different roles, known as adaptive subfunctionalization. Pseudogenes were also found, indicating a potential loss of function in one duplicate due to imbalance. Overall, gene duplication and divergence play a role in the ecological functions of DFR genes in Scutellaria.