Medicine
8 years ago

Sperm protein discovery could revolutionize male infertility treatment

Journal of Assisted Reproduction and Genetics
Sodium-Hydrogen-Exchanger expression in human sperm and its relationship with semen parameters
Zhe Zhang, Yuzhuo Yang, Han Wu, Hongliang Zhang, Haitao Zhang, Jiaming Mao, Defeng Liu, Lianming Zhao, Haocheng Lin, Wenhao Tang, Kai Hong, Hui Jiang

Paper Summary

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The study looked at a protein called sNHE in human sperm to see how it relates to sperm health. They found that sNHE is mainly in the tail of sperm and is linked to sperm concentration and motility. High levels of sNHE were seen in healthy sperm, especially those that swim well. Sperm from men with low motility had lower levels of sNHE. This suggests that sNHE plays a role in sperm movement and may be involved in fertility issues when its levels are off.