Medicine
7 years ago

Split insemination in IVF-ICSI cycles reduces fertilization failure risk.

Daehan saengsik uihak hoeji/Clinical and experimental reproductive medicine
Comparison of clinical outcomes between <i>in vitro</i> fertilization (IVF) and intracytoplasmic sperm injection (ICSI) in IVF-ICSI split insemination cycles
Sun Hee Lee, Jae Hyun Lee, Yong‐Seog Park, Kwang Moon Yang, Chun Kyu Lim

Paper Summary

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The study compared in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) in split insemination cycles. They found that total fertilization failure was more common in IVF, but low fertilization rates were higher in ICSI. ICSI had a higher fertilization rate among injected oocytes, while IVF had a higher rate among retrieved oocytes. Embryo quality before transfer was similar between IVF and ICSI. Split insemination can reduce the risk of total fertilization failure, but unnecessary ICSI is often done in split cycles, potentially leading to more ICSI procedures.