Herbicides can work against each other or with other chemicals, affecting weed control. The level of interference is crucial in deciding if a mix is helpful. Combining herbicides with different targets can cover more types of weeds. Sometimes, interference can actually protect crops. If interference is too strong, factors like herbicide amount, how it works, plant type, and timing need to be managed. These factors are complex and not fully understood. Using herbicide mixes is becoming more important, so understanding interference is key.