The article investigates how chemicals build up in fish by studying 168 organic compounds. It looks at how these chemicals move from water into fish, how they increase as fish eat other organisms, and how they interact with water. The researchers found that some chemicals don't follow the expected patterns. They used special techniques to understand why this happens. They also discovered that using certain rules to identify chemicals that build up in fish through eating can lead to mistakes. This shows the importance of using real data to assess the risks of these chemicals and creating tools to predict how they build up in the environment.