The application of nitrogen fertilizer in maize plays a crucial role in its growth and yield. The timing and method of nitrogen application are key factors that affect the crop's development. Applying the right amount of nitrogen at the right stages of growth, such as planting, knee high, and flowering, is essential for maximizing grain yield. Excessive nitrogen can actually decrease crop yield. Different maize varieties respond differently to nitrogen, with hybrid and improved varieties being more responsive. This review provides valuable insights for maize researchers and growers to make informed decisions about nitrogen application for optimal maize production.