Reserpine Triggers Pain and Depression, Fueling Inflammatory Surge in Rats
The researchers studied how giving rats a drug called reserpine can make them feel pain and depression at the same time. They found that rats injected with reserpine showed signs of pain and depression, like reduced pain tolerance, less interest in sugary treats, and changes in their behavior. The levels of certain inflammatory substances in their blood also increased. This suggests that reserpine injections can mimic the symptoms of pain and depression in rats, making it a useful model for studying these conditions and potential treatments.