Researchers have been looking for new refrigerants that won't harm the ozone layer or contribute to global warming like the old ones did. They've found some new options that are safer but come with other challenges like being flammable and toxic. The scientists reviewed different studies and found that R1234yf could be a good replacement for R134a in fridges and car air conditioners because it's less flammable. They also discovered that R32 could be a good alternative to R410A for cooling systems. These changes could help protect the environment and make our cooling systems safer.