The study looked at how different types of fertilizers affect the growth and yield of bottle gourd plants. They tested eight different treatments on two varieties of bottle gourd plants. The treatment with 25% inorganic fertilizer and 75% vermicompost showed the best results in terms of plant growth, yield, and quality. One of the varieties, C.B.H. 11, performed better with various organic and inorganic fertilizers. Treatment T5 had the highest gross and net returns, while treatment T7 had the best cost benefit ratio. Overall, using a mix of organic and inorganic fertilizers can improve the growth and yield of bottle gourd plants.