Mutations in Spike Protein Make COVID-19 More Aggressive Than SARS
The spike glycoprotein in coronaviruses, like SARS-CoV-2, SARS-CoV, and MERS-CoV, plays a crucial role in how these viruses infect and spread. By analyzing the spike protein sequences and structures, researchers found that mutations in this protein make SARS-CoV-2 more aggressive than other coronaviruses. These mutations also affect how the virus binds to cells and evolves over time. Understanding these differences can help in developing treatments and vaccines for COVID-19.