Earthworms like Eisenia fetida and Metaphire guillelmi can help clean up soil contaminated with antibiotics like chlortetracycline (CTC) and antibiotic resistance genes (ARGs). The earthworms speed up the breakdown of CTC and its byproducts in the soil, reducing the levels of ARGs by 35-44%. They also change the types of bacteria in the soil, promoting helpful bacteria that can break down CTC. This process helps to reduce the risk of antibiotic resistance genes spreading in the environment.