The study looked at how different levels of sperm DNA damage affect the success of a fertility treatment called intracytoplasmic sperm injection (ICSI). They divided patients into groups based on the amount of DNA damage in the sperm and the age and hormone levels of the female partner. The results showed that higher levels of sperm DNA damage did not significantly impact the overall success of ICSI. However, when DNA damage was very high, younger women with better hormone levels had higher pregnancy and live birth rates compared to older women with lower hormone levels. High sperm DNA damage was also linked to poorer semen quality.