Constructed wetlands are an effective and eco-friendly way to treat wastewater. In this study, a two-stage subsurface vertical flow constructed wetland was used to remove Biochemical Oxygen Demand and fecal coliforms from domestic wastewater. The wetland, planted with Scirpus ssp (tule), achieved a 99.99% removal of fecal coliforms and a 94.46% removal of Biochemical Oxygen Demand. Importantly, the removal efficiency remained constant even when the input concentration of contaminants varied. This shows that vertical flow constructed wetlands can efficiently treat wastewater, making them a promising option for sustainable wastewater treatment.