Genomes' Mutation Landscapes Shape Evolution and Adaptation in Surprising Ways
The article discusses how genomes not only have a specific replication rate but also a specific mutation rate, leading to the concept of mutation landscapes. Evolution on mutation landscapes can help organisms adapt and evolve in their environment. The researchers found that the interaction between mutation landscapes and fitness landscapes is crucial for adaptation. Contrary to previous beliefs, at equilibrium, there is not always selection for the minimum mutation rate, but rather for an optimum distribution of mutation rates known as a 'mutational quasispecies'.