The article discusses the rise and fall of ancient kingdoms after the death of Alexander the Great. It covers the events leading up to the Battle of Ipsus in 301 BC, where Antigonus was killed. It also talks about the decline of the Seleucid empire due to Parthian invasions, ending with Pompey's arrival in 64 BC. The Seleucid rulers played a significant role during this period. The Ptolemies, another ruling dynasty, lasted 30 years longer before submitting to Rome, marking the end of the Hellenist kingdoms.