This review investigates why some men struggle with low sperm movement, a common cause of infertility. Problems with energy metabolism are believed to be behind this issue, but the exact pathways are not well understood. By unraveling these cellular and molecular pathways, new treatments might be developed to improve sperm motility in men with this condition. The study explores the reasons for decreased sperm movement, including certain genes and metabolic factors that play a role in this issue. This could open new avenues for tackling male infertility due to poor sperm motility.