Human activities release harmful chemicals that destroy the ozone layer, like chlorofluorocarbons. These chemicals reach the upper atmosphere where they can break down ozone. However, in the Antarctica region, a unique cold air system forms something called a polar stratospheric cloud (PSC) that traps these harmful chemicals in an inactive state. This prevents them from destroying more ozone. This process doesn't happen in other parts of the world, like the Arctic, because the specific conditions needed for PSC formation are rare. Essentially, the ozone hole is mostly contained in the Antarctic stratosphere, which helps protect life on Earth.