The article explores the connection between art and science in the work of M.C. Escher. It delves into Escher's use of symmetry, geometry, and visual perception in his intricate drawings. Researchers discuss Escher's mathematical challenges, classification systems, and the influence of geometry on his designs. They also explore Escher's representation of mathematical ideas and the use of computer graphics to animate his work. The article highlights Escher's unique approach to art, blending elements of mathematics, physics, and biology in his creations.