The article discusses trade and investment in the Asia-Pacific region, focusing on Japan and the Newly Industrialized Economies (NIEs). It explores the shift from competition to cooperation between Japan and the NIEs. The researchers also examine the European presence in Asia, regionalism in world trade, foreign direct investment (FDI) in the Asia-Pacific region, and the involvement of the United States in economic integration in Asia. Key topics include trends in US direct investment in Japan, Japan's official development aid, conflicts between the US and Japan, and trade promotion for small and medium-sized enterprises in Asia and the Pacific. The article provides insights into current situations and future prospects in the region.