The study analyzed organic acid and chemical compositions in tobacco leaves from Henan. Different acids varied greatly, with malic acid being the highest and pentadecanoic acid the lowest. Fumaric acid had the most variation. Chlorine and starch also showed variation. Total nitrogen was the lowest among conventional compositions. Nicotine and potassium were slightly low, while total sugar and reducing sugar were high. Some compositions were too high or low. Potassium had a close relationship with organic acids, while chlorine had little connection.