The article explores how the concept of knowledge economy has shifted from focusing on science-based industries to service-based economies. This change is not just due to global production changes, but also to a new understanding of knowledge as a service or creative activity. The role of scientific research in a service-led knowledge economy is examined, showing how knowledge is now seen as a key driver of economic growth in various intangible economies. This shift has transformed the traditional idea of a knowledge economy from one based on manufacturing to one encompassing service and creative industries.